Toltrazuril CAS 69004-03-1

Product name:Toltrazuril
Cas:69004-03-1
Molecular weight:425.38
Appearance: White or off-white moldable powder
EINECS：614-893-5
Synonyms:Toltrazuril, >=99%; bay-i9142; TOLTRAZURIL; 1-METHYL-3-[3-METHYL-4-[4-(TRIFLUOROMETHYLTHIO)PHENOXY]PHENYL]-1,3,5-TRIAZINE-2,4,6 (1H,3H,5H)-TRIONE; Bayvi 9142;

CAS: 69004-03-1

MF: C18H14F3N3O4S

EINECS: 614-893-5

1.What is Toltrazuril？

Toltrazuril is a triazone compound and a new broad-spectrum special anti-coccidial drug. Toltrazuril is a white or off-white crystalline powder; odorless. Soluble in ethyl acetate or methylene chloride, slightly soluble in methanol, insoluble in water.

Specification

Appearance	Should be white or almost white crystalline powder, odorless	Almost white crystalline powder, odorless
Solubleness	Should dissolved in the ethylacetate orchloroform, sparingly soluble in methanol, insoluble in water	Dissolved in the ethylacetate or chloroform, sparingly soluble in methanol, insoluble in water
Melting point	193℃-196℃	194℃-195℃
IR	Should be concordant with the RS spectrum	Concordant with theRS spectrum
HPLC	The retention time of the main peak of the test solution should be consistent with that of the control solution	Consistent with that of the control solution
Clarity & color	Should be colorless and clear. If it is turbid, it shall not be more intense than standard turbidity solution No. 1.If the color is developed, it shall not be darker than the standard yellow colorimetric solution No.1.	Colorless and clear
Fluorides	≥12.0%	12.5%
Loss on drying	≤0.5%	0.04%
Residue on ignition	≤0.1%	0.02%
Heavy metals	≤0.001%	<0.001%
Assay (Dry)	≥98%	99.6%

Application

1.The mechanism of action of Toltrazuril is to interfere with coccidial cell nuclear division and mitochondria, affect the respiratory and metabolic functions of the worm, and can cause the endoplasmic reticulum to expand and cause severe vacuolization, thus causing the death of coccidia. It mainly affects coccidia. The stages of schizogeny and gametogenesis.
2. Toltrazuril often used as anticoccidial drugs. For the treatment of poultry coccidiosis. This product is effective against Eimeria in chickens, brucella, giant, tender, poisonous and mild; Eimeria in turkeys, Eimeria in turkeys; and Eimeria in geese. It has good inhibitory effect on Eimeria truncatula and Eimeria truncatula.
3. Toltrazuril is an antiprotozoal drug that acts against coccidial parasites. Toltrazuril induces changes in the subtle structure of coccidia during development, mainly due to swelling of the endoplasmic reticulum and Golgi apparatus and abnormalities in the surrounding nuclear space, which interferes with nuclear division. Toltrazuril causes a reduction in parasite respiratory enzymes.