CAS:537-42-8
Molecular Formula:C16H16O3
Molecular Weight:256.3
EINECS:611-041-4
Synonyms:3,5-DIMETHOXY-4′-HYDROXYSTILBENE; 3′,5′-DIMETHOXY-4-STILBENOL; 4-[(1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL]PHENOL; PTEROSTILBENE; PTEROCARPUS MARSUPIUM; TRANS-3,5-DIMETHOXY-4′-HYDROXYSTILBENE; (E)-3,5-Dimethoxy-4′-hydroxystilbene; (E)-3′,5′-Dimethoxystilbene-4-ol; 4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]phenol; 4-[(E)-3,5-Dimethoxystyryl]phenol
Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is a naturally derived compound found primarily in blueberries and Pterocarpus marsupium (PM) heartwood. Pterostilbene is structurally similar to resveratrol, a compound found in red wine that has comparable antioxidant, anti-inflammatory, and anticarcinogenic properties; however, pterostilbene exhibits increased bioavailability due to the presence of two methoxy groups which cause it to exhibit increased lipophilic and oral absorption. In plants, it serves a defensive phytoalexin role.
Pterostilbene has been used:
to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathwayto determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
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