What is 2-Tetrahydrofuroic acid CAS 16874-33-2?
2-Tetrahydrofuroic acid is a colorless to yellow viscous liquid that turns brown when heated or stored for a long time. Boiling point 244 ℃ (736mmHg), flash point 139 ℃. The relative density is 1.1700. Easy to dissolve in water, chloroform, ethyl acetate, etc.
Specification
Item |
Specification |
Boiling point |
128-129 °C13 mm Hg(lit.) |
Density |
1.209 g/mL at 25 °C(lit.) |
Melting point |
21°C |
flash point |
139 °C |
resistivity |
n20/D 1.46(lit.) |
pKa |
3.60±0.20(Predicted) |
Application
2-Tetrahydrofuroic acid can serve as an antagonist of the VLA-4 antigen and also as a chiral resolving agent for the important intermediate of the super influenza drug Xofluza; (S) 2-THFA is the main raw material for preparing chiral adjuvant (S) – acetyltetrahydrofuran, an intermediate for preparing cephalosporin antibiotics, and an important intermediate for preparing hormone releasing hormone LHRH.
Packing
Usually packed in 25kg/drum,and also can be do customized package.