CAS:14976-57-9
녹는점 158-162°C
MF:C25H30ClNO5
기타 이름:141761-83-3 1222-05-5 79673-53-3
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What is of Clemastinefumarate with CAS 14976-57-9?
는 푸마르산염의 clemastine. 항히스타민제와 antimuscarinic 고 적당한 진정성에 사용되는 징후 기복의 알레르기성과 같은 조건이 비염,두드러기,결막염에서의 소양증(심한 가려움증)피부 콘돌리자 이온입니다.
설명
제품 이름: | Clemastine 푸마르산염 |
Synonyms: | CLEMASTINE FUMARATE;CLEMASTINE FUMARATE SALT;(+)-2-(2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrro;(+)-2-(2-((p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrroli;(+)-lfumarate(1:1);1-methyl-2-(2-(methyl-p-chlorodiphenylmethyloxy)ethyl)pyrrolidine;(2R)-2-[2-[(1R)-1-(4-CHLOROPHENYLETHOXY)]ETHYL]-1-METHYL-2-PYRROLIDINE FUMARATE;2-(2-(1-(4-chlorophenyl)-1-phenylethoxy)ethyl)-1-methylpyrrolidine |
CAS: | 14976-57-9 |
MF: | C25H30ClNO5 |
MW: | 459.96 |
EINECS: | 239-055-2 |
제품 카테고리: | antianaphylaxis;TAVIST;Histaminergics;Antagonists;Neurotransmitters;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals |
Mol File: | 14976-57-9.mol |
응용 프로그램
Clemastine fumarate is a selective histamine H1 receptor antagonist (Ki = 0.26 nM) that also displays high affinity for muscarinic receptors (Ki = 16 nM). It has also recently been identified as a positive allosteric modulator of P2X7 receptor signaling. Clemastine fumarate has long been used to inhibit histamine-induced bronchoconstriction in asthma and airway hyperresponsive studies.
포장
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