CAS:1197-18-8
Other Names:Tranexamic acid
MF:C8H15NO2, C8H15NO2
EINECS No.:214-818-2
Synonyms: TIMTEC-BB SBB006715; TRANS-4-AMINOMETHYL-1-CYCLOHEXANECARBOXYLIC ACID; trans-4-aminomethylcyclohexane-1-carboxylate
what is of Tranexamic Acid with CAS 1197-18-8?
Tranexamic Acid with CAS 1197-18-8 is a synthetic derivative of lysine. It is a commonly used hemostatic agent in clinical practice. It plays a hemostatic effect by inhibiting the dissolution of fibrin. Trantranic acid can strongly adsorb Lysine-binding sites of fibrinogen affinity sites on plasminase and plasminogen, and inhibit the binding of plasminogen and fibrin, and thus strongly inhibit the decomposition of fibrin caused by plasminogen. In addition, the antifibrinolytic effect of tranatemic acid was more obvious in the presence of antifibrinolytic enzymes such as macroglobulin in serum
Specification
| Items of Test | Standard as per USP30 |
|
Description |
1.White crystalline powder,Odorless and has a bitter taste |
| 2.Freely soluble in water and glacial Acetic acid; very slightly soluble in ethanol; practically insoluble in Ether | |
| 3.dissolves in sodium hydroxide TS | |
|
Identification |
1.Nimhydrin reaction produces a Deep purple colour |
| 2.the dried precipitate formed with
p-toluenesulfonic acid melts between 265.0℃-266.0℃ |
|
| Clarity of solution | Clear and colourless |
| Chloride | ≤0.014% |
| Heavy metals | ≤10ppm |
| Arsenic | ≤22ppm |
| Readily carbonizable substances | NO colour develops |
| Cis-Isomer | ≤0.8% |
| Loss on drying | ≤0.5% |
| Residue on ignition | ≤0.10% |
| Assay | ≥99.0%of C₈H1sNo₂ (dried) |
Usage
Tranexamic acid is a synthetic derivative of lysine, which is an antifibrinolytic drug and has hemostatic properties
Hemostatic agents have significant effect on traumatic bleeding, and prophylactic medication before surgery can reduce surgical bleeding
Packing
25kgs/drum, 9tons/20’container
25kgs/bag, 20tons/20’container
