CAS: 34157-83-0
Molecular Formula: C29H38O4
Molecular Weight: 450.61
EINECS: 636-472-5
Synonyms: CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(PLEASE CALL); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol
Celastrol is insoluble in water, soluble in dimethyl sulfoxide and anhydrous ethanol. Derived from anti-cancer active ingredients in plants such as Thunder God Vine and South Snake Vine in the family Celastraceae. An effective proteasome inhibitor, confirmed to induce cancer cell apoptosis by inhibiting proteasome activity
| Item | Specification |
| Boiling point | 645.7±55.0 °C(Predicted) |
| Density | 1.2 |
| Melting point | 219-230°C |
| pKa | 4.78±0.70(Predicted) |
| λmax | 424nm(MeOH)(lit.) |
| Storage conditions | -20°C |
Celastrol is used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: It has strong antioxidant properties, anti-cancer angiogenesis effects, and anti rheumatoid effects. An effective proteasome inhibitor, confirmed to induce cancer cell apoptosis by inhibiting proteasome activity
Usually packed in 25kg/drum,and also can be do customized package.
