Trimethylacetic anhydride CAS 1538-75-6

CAS:1538-75-6
Molecular Formula:C10H18O3
Molecular Weight:186.25
EINECS:216-263-1

Synonyms:BIS(TRIMETHYLACETIC) ANHYDRIDE; 2,2-DIMETHYLPROPIONIC ACID ANHYDRIDE; 2,2-DIMETHYLPROPIONIC ANHYDRIDE; 2,2-Dimethylpropionic anhydride, Pivalic anhydride; Bis(2,2-dimethylpropionic acid)anhydride; Bis(2,2-dimethylpropionic)anhydride; Bis(pivalic acid)anhydride; Bis(pivalic)anhydride; Dipivalic anhydride; Pivalic acid anhydride

What is Trimethylacetic anhydride CAS 1538-75-6？

Trimethylacetic anhydride belongs to the class of alkyl anhydride compounds, which can be prepared by dehydration reaction of valeric acid. It has extremely high chemical reactivity and is commonly used as an acylation reagent in the field of organic synthesis chemistry. It can be used for esterification reactions of alcohols and phenolic compounds

Especificação

Item	Especificação
Ponto de ebulição	193 °C(lit.)
Densidade	0.918 g/mL a 25 °C(lit.)
Ponto de inflamação	135 °F
Índice de refração	n20/D 1.409(lit.)
Pureza	Atmosfera inerte,em Temperatura ambiente

Aplicação

Trimethylacetic anhydride is used as an acylation and esterification reagent, which participates in the acylation and esterification reactions with aniline and phenol. Trimethylacetic anhydride is also used in solid-phase oligonucleotide synthesis and kinetic separation of racemic 2-hydroxy – γ – butyrolactone and diphenylacetic acid, for the production of cyano-4, N-tert-butoxycarbonyl piperidine, and in solid-phase oligonucleotide synthesis.