What is Trimethylacetic anhydride CAS 1538-75-6?
Trimethylacetic anhydride belongs to the class of alkyl anhydride compounds, which can be prepared by dehydration reaction of valeric acid. It has extremely high chemical reactivity and is commonly used as an acylation reagent in the field of organic synthesis chemistry. It can be used for esterification reactions of alcohols and phenolic compounds
Specification
Item |
Specification |
Boiling point |
193 °C(lit.) |
Density |
0.918 g/mL at 25 °C(lit.) |
Flash point |
135 °F |
Refractive index |
n20/D 1.409(lit.) |
Purity |
Inert atmosphere,Room Temperature |
Application
Trimethylacetic anhydride is used as an acylation and esterification reagent, which participates in the acylation and esterification reactions with aniline and phenol. Trimethylacetic anhydride is also used in solid-phase oligonucleotide synthesis and kinetic separation of racemic 2-hydroxy – γ – butyrolactone and diphenylacetic acid, for the production of cyano-4, N-tert-butoxycarbonyl piperidine, and in solid-phase oligonucleotide synthesis.
Packing
Usually packed in 25kg/drum,and also can be do customized package.