TROMETAMOL with cas 77-86-1

Other Names:Tris Base
MF:C4H11NO3
EINECS No.:201-064-4
Product name:Tris Base
CAS:77-86-1

CAS: 77-86-1
Purity: 99%
MF: C4H11NO3
TROMETAMOL with cas 77-86-1
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What is  of  TROMETAMOL with cas 77-86-1?

Tris, or tris(hydroxymethyl)aminomethane, or known during medical use as tromethamine or THAM, is an organic compound with the formula (HOCH2)3CNH2. It is extensively used in biochemistry and molecular biology as a component of buffer solutions such as in TAE and TBE buffers, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes. Tris also complexes with metal ions in solution. In medicine, tromethamine is occasionally used as a drug, given in intensive care for its properties as a buffer for the treatment of severe metabolic acidosis in specific circumstances. Some medications are formulated as the “tromethamine salt” including hemabate (carboprost as trometamol salt), and “ketorolac trometamol”.

Specification

Item
Specifications
Results
Content
99.5%—101.0%
100.34%
Moisture
(by karl fischer)
≤0.3%
0.19%
Insolubles
≤0.005%
0.00%
PH(5%)
10.0-11.5
10.65
UV Absorbance
(290nm,40%)
≤0.2
0.050
UV Absorbance
(400nm 40%)
≤0.2
0.011
Heavy metals(as pb)
≤5ppm
<5ppm
Fe
≤5ppm
<5ppm
Cl
≤3ppm
<5ppm
Solubility (1.0M solution in water)
Immediately soluble yielding a clear haze-free solution free of particulates
Residue on ignition
≤0.05%
0.00%
Melting point(℃)
168.0-172.0
171.5-171.9
Appearance
White crystal powder
Conclusion
The results conforms with Enterprise standards

Application

In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals. As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning Compounds, so-called soluble oils. Absorbent for acidic gases. Biological buffer.

Packing

25kgs/drum, 9tons/20’container

TROMETAMOL with cas 77-86-1
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