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CAS:124-20-9
MF:C7H19N3
EINECS:204-689-0
Purity:99%
Brand Name:Unilong
Other Names:Spermidine
what is Spermidine CAS 124-20-9?
Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 μM) inhibits the activity of the human inward-rectifying potassium channel Kir2.3 in a patch-clamp assay. It induces autophagy in HeLa cells when used at a concentration of 100 μM and increases the lifespan of D. melanogaster, yeast, and C. elegans. Spermidine (30 mM in the drinking water) reduces demyelination of the optic nerve and disease severity in a mouse model of experimental autoimmune encephalomyelitis (EAE). It reduces increases in blood pressure, left ventricular posterior wall thickness, and heart weight in salt-sensitive Dahl rats fed a high-salt diet, a model of hypertension-induced congestive heart failure. Formulations containing spermidine have been used as dietary supplements.
Specification
|
Melting point
|
23-25 °C
|
|
Boiling point
|
128-130 °C (14 mmHg)
|
|
density
|
1.00 g/mL at 20 °C
|
|
refractive index
|
n20/D 1.479(lit.)
|
|
Fp
|
>230 °F
|
|
storage temp.
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2-8°C
|
|
solubility
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H2O: 1 M at 20 °C, clear, colorless
|
|
pka
|
10.53±0.19(Predicted)
|
|
Specific Gravity
|
0.925
|
Usage
Spermidine with cas 124-20-9 can be used in Biochemical and molecular biological reagents.
Packing
25kgs/drum, 9tons/20’container.
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