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CAS:3886-70-2
Molecular Formula:C12H13N
Molecular Weight:171.24
EINECS:223-425-5
Synonyms:(R) 1-(1-NAPTHYL)ETHYLAMINE; (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE; (R)-1-(1-NAPHTHYL)ETHYLAMINE; (R)-1-(NAPHTHALEN-1-YL)ETHANAMINE; (R)-(+)-1-(NAPHTHYL)ETHYLAMINE; (R)-(+)-A-(1-NAPHTHYL)ETHYLAMINE
1.Quick details of R-Napthylethylamine with CAS 3886-70-2
(R) – (+) -1- (1-Naphthyl) ethylamine is a light yellow to brown transparent liquid, stable at room temperature and pressure, and sensitive to air; Insoluble in acids, oxidants, anhydrides, chloroformate esters, and acyl chlorides. Intermediate of the drug cinacalcet, which is used to treat secondary hyperparathyroidism in patients with chronic kidney disease (CKD) undergoing dialysis and to treat hypercalcemia in patients with parathyroid cancer; Sina Kase intermediate.
2.Description of R-Napthylethylamine with CAS 3886-70-2
| Item |
Standard |
Test Results |
| Identification | A.H-NMR:Comply with the structure | Complies |
| B.LC-MS:Comply with the structure | Complies | |
| C.The IR spectrum of sample should be identical with that of reference standard. | Complies | |
| D.HPLC-ESI-MS
The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay. |
Complies | |
| Loss on drying | ≤2.0% | 0.19% |
| Heavy metals | ≤10 ppm | <10ppm |
| Water | ≤1.0% | 0.1% |
| Sulphated ash | ≤0.5% determined on 1.0 g. | 0.009% |
| Residue on ignition | ≤0.1% | 0.03% |
| Related Substances | Unspecified impurities: for each impurity ≤0.10% | <0.10% |
| Total Impurity ≤0.5% | 0.18% | |
| Purity | ≥99.0% | 99.7% |
| Assay | 99.0%~101.0% (anhydrous substance). | 99.8% |
| Storage | Preserve in well-closed, light-resistant and airtight containers. | Complies |
3.Application
(R)-(+)-1-(1-Naphthyl)ethylamine is used in chiral synthesis in organic reactions including the synthesis of β-amino acids and the enantioselective of ketones to nitroolefins.
4.Packing
Usually packed in 25kg/drum,and also can be do customized package
5.Synonyms
(R) 1-(1-NAPTHYL)ETHYLAMINE; (R)-(+)-1-(1-NAPHTHYL)ETHYLAMINE; (R)-1-(1-NAPHTHYL)ETHYLAMINE; (R)-1-(NAPHTHALEN-1-YL)ETHANAMINE; (R)-(+)-1-(NAPHTHYL)ETHYLAMINE; (R)-(+)-A-(1-NAPHTHYL)ETHYLAMINE
