N-Oleoylethanolamine with cas 111-58-0

what is of N-Oleoylethanolamine with cas 111-58-0

Oleoyl ethanolamide (OEA) is an analog of the endocannabinoid AEA found in brain tissue and in chocolate. It is one of the long chain fatty acid ethanolamides that accumulates rapidly in infarcted tissue, but its biosynthesis is reduced in the intestine of rats following food deprivation. OEA is an endogenous, potent agonist for PPARα, exhibiting an EC₅₀ value of 120 nM in a transactivation assay. Systemic administration of OEA suppresses food intake and reduces weight gain in rats (10 mg/kg intraperitoneally) and PPARα wild-type mice, but not in PPARα knockout mice. These data indicate that OEA regulates food intake by a PPARα-mediated mechanism.

CAS: 111-58-0

Purity: 99.95%

MF: C20H39NO2

Quick Details of N-Oleoylethanolamine with cas 111-58-0

CAS No.:111-58-0
Other Names:N-Oleoylethanolamine
MF:C20H39NO2
EINECS No.:203-884-8
Place of Origin:Shandong, China
Type:Dyestuff Intermediates
Purity:99.95%
Brand Name:Unilong
Model Number:JL20210027
Application:research, research
Appearance:white powder
Product name:N-Oleoylethanolamine
CAS:111-58-0
Shelf life:2 Years
MOQ:1kg
Packing:25kg/drum
molecular formula:C20H39NO2
EINECS:203-884-8
Delivery:Immediately
Color:white powder

Specification of N-Oleoylethanolamine with cas 111-58-0

CAS	111-58-0
MF	C20H39NO2
MW	325.53
EINECS	203-884-8
Melting point	63-64 °C
Boiling point	496.4±38.0 °C
Density	0.915±0.06 g/cm3
Pka	14.49±0.10
Storage	Cool Dry Place
Appearance	White powder
MOQ	1kg
Samples	Available
Shelf life	2 Years

Packing of N-Oleoylethanolamine with cas 111-58-0

25kgs/drum, 9tons/20’container

Usage of N-Oleoylethanolamine with cas 111-58-0

N-?Oleoylethanolamide is an agonist of peroxisome proliferator-activated receptor-α (PPAR-?α). N-?Oleoylethanolamide generates an intestinal signal that stimulates central dopamine activity establishing a link between caloric-?homeostatic and hedonic-?homeostatic controllers. Oleoylethanolamide has been implicated as the molecular mechanism associated with gastric bypass success. N-?Oleoylethanolamide is a selective GPR55 agonist.