N-Hydroxyphthalimide CAS 524-38-9

CAS: 524-38-9
Molecular Formula: C8H5NO3
Molecular Weight: 163.13
EINECS: 208-358-1
Storage Period: 2 year

Synonym: TIMTEC-BBSBB009098; N-HYDROXY-PHTALIMIDE; N-HYDROXYPHTHALIMIDE; 2-hydroxy-1h-isoindole-3(2h)-dione; N-Hydroxyphehtalimide; N-HYDROXYMETHYL-3-METHYLOXETANE; N-Hydroxyphthalimide(Nop)

What is N-Hydroxyphthalimide CAS 524-38-9？

N-Hydroxyphthalimide is used in the synthesis of a new class of antibacterials potent against macrolide resistant bacteria. Also used in the synthesis of pyrazolidines, isoxazolidines and tetrahydrooxazines.

Specification

Item	Value
Product name	N-Hydroxyphthalimide
Cas number	524-38-9
Melting point	233 °C (dec.) (lit.)
Boiling point	290.19°C (rough estimate)
density	1.64 g/cm3
refractive index	1.5510 (estimate)
storage temp.	Store at RT.
pka	6.10±0.20(Predicted)
form	Powder
Water Solubility	Slightly soluble in water.
pka	9.85(at 20℃)
Water Solubility	0.29 g/100 mL (20 ºC)

Application

Aerobic oxidation of various alcohols has been accomplished by using a new catalytic system, N-hydroxyphthalimide (NHPI) combined with Co (acac). A practical catalytic method to convert alkylbenzenes into the corresponding carboxylic acids under atmospheric dioxygen at ambient temperature using a combined catalytic system consisting of N-hydroxyphthalimide (NHPI) and Co (OAc) 2 was developed.