Metronidazole CAS 443-48-1

CAS: 443-48-1
Molecular Formula: C6H9N3O3
Molecular Weight: 171.15
EINECS: 207-136-1

Synonyms: TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol,2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol; 2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

Metronidazole CAS 443-48-1
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What is Metronidazole CAS 443-48-1?

Metronidazole (CAS 443-48-1) is a synthetic nitroimidazole derivative widely used as an antibacterial and antiprotozoal agent. It is highly effective against anaerobic bacteria and protozoa, making it an essential pharmaceutical ingredient in both human and veterinary medicine. With its broad antimicrobial spectrum and proven clinical safety, Metronidazole has been one of the most important active pharmaceutical ingredients (APIs) for decades.

It is available in multiple forms, including powders, tablets, capsules, topical gels, and injectable solutions, depending on treatment needs.

Specification

Item Specification
Boiling point 301.12°C (rough estimate)
Density 1.3994 (rough estimate)
Melting point 159-161 °C (lit.)
pKa pKa 2.62(H2O,t =25±0.2,
Storage conditions 2-8°C

Applications of Metronidazole

Metronidazole is a versatile compound used in a wide range of therapeutic applications:

1. Human Medicine

Treatment of anaerobic bacterial infections.

Management of protozoal infections such as giardiasis, trichomoniasis, and amoebiasis.

Used in combination therapies for Helicobacter pylori infections in gastric ulcers.

Topical formulations for rosacea and bacterial vaginosis.

Dental medicine for periodontal infections.

2. Veterinary Medicine

Treatment of gastrointestinal infections in pets and livestock.

Management of anaerobic infections in veterinary practice.

3. Pharmaceutical Manufacturing

Active ingredient in oral solid dosage forms (tablets, capsules).

Used in injectable formulations for hospital treatments.

Incorporated into topical creams and gels.

Packing

Usually packed in 25kg/drum,and also can be do customized package.

Metronidazole CAS 443-48-1 package

Metronidazole CAS 443-48-1
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