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Madecassic acid with CAS 18449-41-7

what is of  Madecassic acid with CAS 18449-41-7?

Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.

1.Quick details of Madecassic acid with CAS 18449-41-7

Type:Herbal Extract
Variety:Madecassic Acid
Extraction Type:Solvent Extraction
Packaging:bottle, Drum, Glass Container, Plastic Container, Vacuum Packed
Place of Origin:Hunan, China
Model Number:Madecassic Acid
Product Name:Madecassic Acid
Active Ingredient:Madecassic Acid
Molecular Formula:C30H48O6
Molecular Weight:504.70
Appearance:white powder
part:whole herb

2.Description of  Madecassic acid with CAS 18449-41-7

Product Name gotu kola extract madecassic acid 90% for cosmetics
Brand OEM, ODM, or our brand
Used Part whole herb
Extract Solvent Ethanol
Storage Life Up to 2 years
OEM Accepted
Storage Method Stored in a cool and dry well-closed container,keep away from moisture and strong light/heat


Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells.