LICOCHALCONE-A with CAS 58749-22-7

CAS:58749-22-7
Molecular Formula:C21H22O4
Molecular Weight:338.4
EINECS:635-678-2
Synonyms:4,4′-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone; Glycyrrhiza chalcone A; Licorice Chalcone A; Licoricchalcone A; Licochalcone A (10mg)

CAS: 58749-22-7
MF: C21H22O4
Purity: 99%
LICOCHALCONE-A with CAS 58749-22-7
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1.what is of  LICOCHALCONE-A with CAS 58749-22-7?

An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.

2.Description of LICOCHALCONE-A with CAS 58749-22-7

Melting point 100°
Boiling point 532.6±50.0 °C(Predicted)
density 1.171±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 7.82±0.15(Predicted)
form Yellow solid
BRN 4534154
InChIKey KAZSKMJFUPEHHW-DHZHZOJOSA-N

3.Application

Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.

4.Packing

25kgs/drum,9tons/20’container

25kgs/bag,20tons/20’container

Glabridin -pack

5.Synonyms

4,4′-Dihydroxy-3-alpha,alpha-dimethylallyl-6-methoxychalcone; Glycyrrhiza chalcone A; Licorice Chalcone A; Licoricchalcone A; Licochalcone A (10mg)

LICOCHALCONE-A with CAS 58749-22-7
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