CAS:53-84-9
MF:C21H27N7O14P2
MW:663.43
EINECS:200-184-4
Synonyms:OSTEOPONTIN,GSTFUSION; )-1-beta-d-ribofuranosylpyridiniumhydroxide,innersalt; adenine-nicotinamidedinucleotide
What is β-Nicotinamide adenine dinucleotide CAS 53-84-9?
Nicotinamide adenine dinucleotide (abbreviated NAD), also known as diphosphopyridine nucleotide (abbreviated DPN), or codehydrogenase I or Coenzyme I. In mammals, there are two states of oxidation type (NAD+) and reduced type (NADH), oxidation type (NAD+) has the maximum ultraviolet absorption spectrum at 260nm, through various deaminases, accepting a hydrogen atom and an electron from the substrate, becoming reduced type, and has the maximum absorption at 340nm. Beta-nicotinamide adenine dinucleotide is used as a coenzyme in REDOX reactions, as a donor of the ribose portion of ADP in the ribosylation of ADP, and as a precursor of the second messenger molecule cyclic ADP ribose. Beta-nicotinamide adenine dinucleotides also act as substrates for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
Specification
Item | Specification |
Melting point | 140-142 °C (decomp) |
Specific rotation | D20 -31.5° (c = 1.2 in water) |
PH | 3.0 (50mg/mL in water) |
Solubility | H2O:50 mg/mL |
Application
Beta-nicotinamide adenine dinucleotide is an essential coenzyme used in biochemical research, clinical diagnosis, clinical drugs and drug research. Nicotinamide adenine dinucleotide is a kind of coenzyme drug. Clinically, it is mainly used for the auxiliary treatment of coronary heart disease, which can improve chest tightness, angina pectoris and other symptoms. The side effects were dry mouth, dizziness, nausea and so on. β-Nicotinamide adenine dinucleotide is involved in energy metabolism and material metabolism in the body, which is conducive to cell repair and renewal. β-Nicotinamide adenine dinucleotide is used in the treatment of coronary heart disease, myocarditis, leukopenia and other diseases.
Packaging
1KG/Bag; 10KG/Bag; 20KG/Drum.
Related keywords
adenosine5’-(trihydrogendiphosphate),p’.fwdarw.’-esterwith3-(aminocarbonyl; beta-diphosphopyridine; cozymasei; enzopride.