Hydroxypropyl beta cyclodextrin with cas 128446 35 5

2-Hydroxypropyl-β-cyclodextrin with CAS 128446-35-5

CAS No.:128446-35-5
Other Names:Hydroxypropyl-beta-cyclodextrin
MF:C63H112O42
EINECS No.:603-269-8

synonym: beta-cyclodextrin,2-hydroxypropylether;(2-Hydroxypropyl)-^b-cyclodextrin,avge.MWca1340;(2-Hydroxypropyl)-^b-cyclodextrin,avge.MWca1400;Hydroxypropyl-beta-cyclodextrin,97Chemicalbook%;(2-Hydroxypropyl)-beta-cyclode;(2-Hydroxypropyl)-beta-cyclodextrin,avge.MWca1400;(2-Hydroxypropyl)-beta-cyclodextrin,MWca1250-1480;(2-Hydroxypropyl)-β-cyclodextrin,97%

What is 2-hydroxypropyl-β-cyclodextrin CAS 128446-35-5?

(2-Hydroxypropyl)-β-cyclodextrin CAS 128446-35-5, a hydroxyalkyl derivative, finds application as a formulation vehicle that is used to enhance the solubility of the drugs in aqueous solutions for the successful delivery of medical agents to biological systems. It is generally employed as a substitute for α-, β- and γ-cyclodextrins.

Specification

Item		Standard
Appearance		White or almost white,amorphous or crystalline powder
Solubility		Freely soluble in water and in propylene glycol
Identification	IR	The spectrum obtained with the substance to be examined shows the same absorption bands as the spectrum obtained with hydroxypropylbetadex CRS
Appearance of solution		The solution is clear and colorless
Conductivity(μS·cm-1)		≤200
Impurity A(%)		≤1.5
Sum of impurities other than A(APLC)(%)		≤1.0
Impurity B(GC)(%)		≤2.5

Application

2-Hydroxypropyl-β-cyclodextrin (HBC) CAS 128446-35-5 is a widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with 2-Hydroxypropyl-β-cyclodextrin.

2-Hydroxypropyl-β-cyclodextrin CAS 128446-35-5-application