CAS: 9007-49-2/68938-01-2
Molecular Formula: C15H31N3O13P2
Molecular Weight:523.37
EINECS:2017-001-1
Storage Period:2 years
Synonyms:Polynucleotide; PN; Sodium DNA; Polydeoxyribonucleotide; PDRN; Calcium DNA; Magnesium DNA; Zinc DNA; Deoxyribonucleic Acid;Deoxyribonucleic Acid(Herringsperm); THYMUSNUCLEICACID; deoxyribonucleicac;
Pharmaceutical Grade Salmon PN CAS 9007-49-2/68938-01-2
PN (Polynucleotide, CAS No. 9007-49-2) is a natural macromolecular DNA polymer derived from pure natural salmon testicular tissue through rigorous purification. Sharing over 98% structural similarity with human DNA, PN exhibits excellent natural skin affinity, leaves no residues after application, and allows for long-term safe use. Featuring a higher molecular weight and larger molecular structure than PDRN, PN possesses a stable three-dimensional scaffold structure that delivers reliable physical filling performance. Its slow degradation profile also enables sustained and long-term skin improvement with outstanding safety and stability.
Specification
| Appearance | White or off-white powder or fibrous solid |
| Solubility | Slightly soluble in water |
| Identification | UV:Ratio of absorbance at 260 and 280nm
1.5-2.0 |
| pH | 5.0-9.0 |
| Average Molecular Weight | ≥1000kD |
| Protein content | <1.0% |
| Loss on Drying | ≤20.0% |
| Heavy metal | ≤10ug/g |
| Transmittance | ≥96.0% |
| Ethanol Residue | <0.5% |
| Bacterial endotoxin | <0.5EU/mg |
| Total aerobic microbial count | NMT 100cfu/g |
| Total molds and yeast count | NMT 100cfu/g |
| Staphylococcus aureus | Negative |
| Pseudomonas aeruginosa | Negative |
| Escherichia coli | Negative |
| ASSAY | ≥95.0% |
Application
Pharmaceutical Grade PN (Polynucleotide, CAS No. 9007-49-2) is purified from salmon reproductive cells via sophisticated separation and optimization technologies to obtain high-purity polymeric nucleotides. Boasting excellent anti-inflammatory, repairing and regenerative efficacy, it effectively accelerates cell regeneration and boosts collagen synthesis. Widely applied in personal care and medical aesthetics, PN serves as a premium regenerative repair conditioner, skin softener and brightening agent for professional skincare treatments.
Features
PN features an average molecular weight of over 1500 KDa and is primarily used for anti-aging firming, anti-inflammatory soothing, skin repair and nourishment, as well as three-dimensional skin filling.
Core Efficacy Mechanisms
1. Tissue Repair and Regeneration: Accelerates the proliferation and migration of fibroblasts, and promotes the synthesis of collagen and elastin to restore damaged skin tissues.
2. Vascular Proliferation and Microcirculation Improvement: Stimulates the proliferation of vascular endothelial cells, optimizes local microcirculation, and delivers sufficient oxygen and nutrients to damaged skin areas.
3. Anti-inflammatory Effect: Modulates the expression of inflammatory factors, relieves tissue inflammatory responses, and builds a favorable skin environment for tissue repair.
4. Cell Protection: Mitigates oxidative stress-induced damage and preserves cell vitality and activity.
Packaging
50g/bottle.100g/bottle.1kg/bag.
Storage
Environment: Cool, dry, well-ventilated, and protected from light storage room
Sealed against moisture, strictly prohibited from getting wet
Stored separately, not mixed with acids, alkalis, or corrosive materials












