Famciclovir CAS 104227-87-4

CAS: 104227-87-4
Molecular Formula: C14H19N5O4
Molecular Weight: 321.33
EINECS: 630-411-6

Synonyms: 2-[2-(2-amino-9H-purin-9-yl)ethyl]-1,3-propanediol 1,3-diacetate; [2-(acetoxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate; Famciclovir>; Famciclovir Famciclovir; Famciclovir HCL; 1,3-Propanediol, 2-[2-(2-amino-9H-purin-9-yl)ethyl]-, 1,3-diacetate; Famciclovir USP/EP/BP; Famciclovir(BRL 42810); Famciclovir D6

Famciclovir CAS 104227-87-4
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What is Famciclovir CAS 104227-87-4?

Famciclovir (CAS 104227-87-4) is a guanine derivative widely recognized as an important antiviral active pharmaceutical ingredient (API). With the molecular formula C₁₄H₁₉N₅O₄ and a molecular weight of 321.34 g/mol, it appears as a white to off-white crystalline powder. Famciclovir is sparingly soluble in water but dissolves well in ethanol, methanol, and other organic solvents.

Famciclovir is the oral prodrug of penciclovir, which means it is rapidly converted into penciclovir after administration in the human body. Penciclovir acts by inhibiting viral DNA polymerase, thereby blocking the replication of herpes viruses. Because of its high oral bioavailability and safety profile, Famciclovir has become a preferred choice in the pharmaceutical industry.

As an API and pharmaceutical raw material, Famciclovir is included in various pharmacopoeias and is widely used in large-scale drug manufacturing.

Specification

Item Specification
Boiling point 550.2±60.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
Melting point 102-104°C
λmax 310nm(EtOH)(lit.)
pKa 4.00±0.10(Predicted)
Storage conditions 2-8°C

Application

  • Antiviral API: Famciclovir is a core raw material for the production of oral antiviral drugs, typically in tablet or capsule form.

  • Treatment of Herpes Simplex Virus (HSV): Used in the treatment of recurrent cold sores and genital herpes caused by HSV-1 and HSV-2.

  • Treatment of Herpes Zoster (Shingles): Famciclovir effectively inhibits the varicella-zoster virus (VZV), helping relieve symptoms and shorten healing time.

Packing

Usually packed in 25kg/drum,and also can be do customized package.

Famciclovir CAS 104227-87-4 package

Famciclovir CAS 104227-87-4
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