2-Tetrahydrofuroic acid CAS 16874-33-2

CAS:16874-33-2
Molecular Formula:C5H8O3
Molecular Weight:116.12
EINECS:605-530-1

Synonyms:2-Furoic acid, tetrahydro; TIMTEC-BB SBB004298; THFAC; 2-TETRAHYDROFURAN CARBOXYLIC ACID FOR SY; 3-tetrahydrofuran-carboxylic acid; Tetrahydro-2-furoic acid 97%; 2-Tetrahydrofuran carboxylic acid for synthesis; Terazosin Impurity 1; Terazosin Impurity19; (2R)-2-oxolanecarboxylate; Terazosin Impurity 21

What is 2-Tetrahydrofuroic acid CAS 16874-33-2？

2-Tetrahydrofuroic acid is a colorless to yellow viscous liquid that turns brown when heated or stored for a long time. Boiling point 244 ℃ (736mmHg), flash point 139 ℃. The relative density is 1.1700. Easy to dissolve in water, chloroform, ethyl acetate, etc.

Спецификация

Предмет	Спецификация
Температура кипения	128-129 °C13 mm Hg(lit.)
Плотность	1.209 g/mL at 25 °C(lit.)
Температура плавления	21°C
температура вспышки	139 °C
удельное сопротивление	n20/D 1.46 (лит.)
пКа	3.60±0.20(Predicted)

Применение

2-Tetrahydrofuroic acid can serve as an antagonist of the VLA-4 antigen and also as a chiral resolving agent for the important intermediate of the super influenza drug Xofluza; (S) 2-THFA is the main raw material for preparing chiral adjuvant (S) – acetyltetrahydrofuran, an intermediate for preparing cephalosporin antibiotics, and an important intermediate for preparing hormone releasing hormone LHRH.