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CAS:537-42-8
Fórmula Molecular:C16H16O3
Peso Molecular:256.3
EINECS:611-041-4
Synonyms:3,5-DIMETHOXY-4′-HYDROXYSTILBENE; 3′,5′-DIMETHOXY-4-STILBENOL; 4-[(1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL]PHENOL; PTEROSTILBENE; PTEROCARPUS MARSUPIUM; TRANS-3,5-DIMETHOXY-4′-HYDROXYSTILBENE; (E)-3,5-Dimethoxy-4′-hydroxystilbene; (E)-3′,5′-Dimethoxystilbene-4-ol; 4-[(E)-2-(3,5-Dimethoxyphenyl)vinyl]phenol; 4-[(E)-3,5-Dimethoxystyryl]phenol
Pterostilbene (trans-3,5-dimetoxi-4-hydroxystilbene) é um composto de origem natural encontrada principalmente em mirtilos e Pterocarpus marsupium (PM) de cerne. Pterostilbene é estruturalmente semelhante ao resveratrol, um composto encontrado no vinho tinto que tem comparável antioxidante, anti-inflamatório, e anticarcinogenic propriedades; no entanto, pterostilbene apresenta maior biodisponibilidade, devido à presença de dois grupos metoxi que causa a apresentar maior lipofílico e a absorção oral. Em plantas, que serve de defesa phytoalexin papel.
Pterostilbene foi usado:
to investigate its anti-oxidative stress activities and the involvement of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-antioxidant response element (ARE) signaling pathwayto determine its effects on transcriptional activation of estrogen receptor-α (ERα) in hormone resistant breast cancer cells)
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