PHMB CAS 32289-58-0

CAS: 32289-58-0
Pureza: 99%
Molecular Formula: (C8H17N5)n.xClH
Molecular Weight: 213.32312
EINECS: 1308068-626-2

Synonyms: PHMB(20%); Polyhexamethyl; PHMB; Biguanide PHMB; Polyhexamethylene biguanidine hydrochloride,~20% in water; PHMB 98%, 20% solution (Polyhexamethylene biguanide hydrochloride); 20% solution; 98% powder

PHMB CAS 32289-58-0
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What is PHMB CAS 32289-58-0?

PHMB CAS 32289-58-0 is best known for its broad-spectrum antimicrobial and antifungal activity. It is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu (Bauch & Lomb, Rochester, NY). PHMB is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.

Especificação

Item
Especificações
Aparência
white to beige powder or solid
Odor
Sem odor
Solubilidade em água
Completa dissolução
Principal ativo componentsand conteúdo(w/w)
PHMB19%~21%
Densidade(a 20℃)
1.039~totaliza 1,046 g/cm3
Valor de PH(20℃)
4.0~6.0
Absorvância(237nm)
≥400
Absorvância (237nm/222nm)
1.2~1.6

Aplicação 

1. Water treatment field (one of the core applications)

Industrial water treatment: As a bactericide and algaecide for circulating cooling water and central air conditioning water systems, PHMB CAS 32289-58-0 effectively inhibits the growth of bacteria, fungi and algae in water, prevents the formation of biofilm (biofilm), avoids pipe blockage and equipment corrosion, and does not affect the pH balance of water quality. It does not require frequent adjustment and has a wide range of applications (replacing traditional chlorine-based bactericides) Reduce the pollution of chlorine residues to the environment.

Drinking water treatment: Some countries (such as the European Union and China) have approved it as an auxiliary component of drinking water disinfectants. At low concentrations, it can kill pathogenic bacteria in drinking water (such as Escherichia coli, Salmonella, Legionella, etc.) without any odor or harmful by-products (such as trichloromethane), enhancing the safety of drinking water.

Swimming pool/aquarium water treatment: PHMB CAS 32289-58-0 is used for sterilization and disinfection in swimming pools, hot springs and aquariums, inhibiting the reproduction of harmful microorganisms. At the same time, it has less irritation to human skin and eyes and is superior to traditional chlorine-containing disinfectants.

2. Medical and health care field

Medical disinfectants/antibacterial materials

Skin and mucous membrane disinfection: Polyhexamethylene biguanide is used for rinsing and disinfecting wounds and mucous membranes (such as the oral cavity and vagina), killing bacteria on the wound surface and preventing infection (such as the core component of gynecological washes, oral mouthwashes, and wound rinses).

Medical device disinfection: Polyhexamethylene biguanide, as a non-invasive disinfectant for medical devices such as endoscopes and ultrasound probes, efficiently kills bacteria without causing corrosion to the devices.

Antibacterial dressings/consumables: Added to medical gauze, cotton swabs, wound dressings, disposable gloves and other materials, they endow them with long-lasting antibacterial functions and reduce the risk of cross-infection.

Drug excipients: Polyhexamethylene biguanide is a preservative used in topical preparations (such as ointments, gels, and eye drops), which inhibits microbial contamination in the preparations, extends the product’s shelf life, and has low irritation to the human body, making it suitable for use on sensitive areas.

3. In the field of daily chemicals and cosmetics

Cosmetic preservatives: Polyhexamethylene biguanide is used in products such as toner, lotion, face cream, shampoo, conditioner and mask, effectively inhibiting the growth of bacteria and fungi (such as mold and yeast) in cosmetics. poly(hexamethylenebiguanide)hydrochloride prevents product deterioration. Moreover, it has strong compatibility (does not conflict with most cosmetic ingredients), no odor, and does not affect the skin feel of the product. It is an ideal alternative to traditional preservatives (such as parabens and formaldehyde releasers).

Personal care products: Used in antibacterial hand sanitizers, body washes, oral care products (toothpaste, mouthwash), feminine care lotions, etc. Through bactericidal effects, it reduces harmful microorganisms on the skin, mouth, and private parts, prevents unpleasant odors and inflammation, and is gentle and non-irritating to the skin and mucous membranes.

4. Other fields

Textile and leather industry: As an antibacterial finishing agent, it is added to textiles (such as underwear, socks, medical clothing, bedding) and leather products (such as leather shoes, handbags), endowing the materials with long-lasting antibacterial functions. poly(hexamethylenebiguanide)hydrochloride can inhibit the unpleasant odors and mold caused by bacterial growth Extend the service life of the product.

Food processing and packaging: PHMB CAS 32289-58-0 is used for disinfection of food processing equipment, workshop floors and walls to kill pathogenic bacteria on food contact surfaces. It can also be used as an antibacterial additive for food packaging materials (such as cling film and food packaging bags). PHMB CAS 32289-58-0 inhibits the reproduction of microorganisms in the packaging and extends the shelf life of food (it needs to meet food-grade safety standards).

In the agricultural field: PHMB CAS 32289-58-0 is used for the preservation and disinfection of crops and fruits and vegetables (such as soaking fruits and vegetables after harvest to kill surface pathogenic bacteria and extend the preservation period). poly(hexamethylenebiguanide)hydrochloride can also be used as a disinfectant in aquaculture water bodies, inhibiting harmful microorganisms in the water, improving the aquaculture environment, and reducing diseases in aquatic animals.

Embalagem 

25kgs/tambor, 9tons/20'container

PHMB CAS 32289-58-0 package

PHMB CAS 32289-58-0
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