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Metronidazole CAS 443-48-1

Name: Metronidazole CAS 443-48-1 - Chemical Supplier Unilong
Brand: Organic Chemistry

CAS:443-48-1
Molecular Formula:C6H9N3O3
Molecular Weight:171.15
EINECS:207-136-1

Synonyms:TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol,2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol; 2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

What is Metronidazole CAS 443-48-1？

Metronidazole is a white or slightly yellow crystalline or crystalline powder; There is a slight odor, with a bitter and slightly salty taste. Slightly soluble in ethanol, slightly soluble in water or chloroform, and extremely slightly soluble in ether. Metronidazole is a nitrogen-containing heterocyclic compound with alkalinity and low water solubility. According to the prodrug principle, metronidazole is made into potassium phosphate ester, which increases its water solubility and can be used as an injection solution.

Especificação

Item	Especificação
Ponto de ebulição	301.12°C (rough estimate)
Densidade	1.3994 (rough estimate)
Ponto de fusão	159-161 °C (lit.)
os valores de pKa	pKa 2.62(H2O,t =25±0.2,
Condições de armazenamento	2-8°C

Aplicação

Metronidazole has a strong antibacterial effect on most anaerobic bacteria and is used to treat amoebiasis, trichomoniasis, and anaerobic bacterial infections. It is also used to treat vaginal trichomoniasis and has been used for intestinal and extraintestinal amoebiasis since 1970. Its efficacy is high, toxicity is low, and it is widely used. Has mutagenic and teratogenic effects on animal experiments.