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CAS:18449-41-7
Molecular Formula:C30H48O6
Molecular Weight:504.71
EINECS:240-851-7
Synonyms:Hydroxy asiaticoside; MADECASSIC ACID(P); 6BETA-HYDROXYASIATIC ACID; 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid; 6-Hydroxyasiatic acidMadecasoside; Madecassic acid, 98%, from Centella asiatica (L.) Urb; Madecassic acid, froM Centella asiatica
1.what is of Madecassic acid with CAS 18449-41-7?
Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.
2.Description of Madecassic acid with CAS 18449-41-7
5.Synonyms
Hydroxy asiaticoside; MADECASSIC ACID(P); 6BETA-HYDROXYASIATIC ACID; 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid; 6-Hydroxyasiatic acidMadecasoside; Madecassic acid, 98%, from Centella asiatica (L.) Urb; Madecassic acid, froM Centella asiatica
