CAS:16874-33-2
Molecular Formula:C5H8O3
Moleculaire Gewicht:116.12
EINECS:605-530-1
Synonyms:2-Furoic acid, tetrahydro; TIMTEC-BB SBB004298; THFAC; 2-TETRAHYDROFURAN CARBOXYLIC ACID FOR SY; 3-tetrahydrofuran-carboxylic acid; Tetrahydro-2-furoic acid 97%; 2-Tetrahydrofuran carboxylic acid for synthesis; Terazosin Impurity 1; Terazosin Impurity19; (2R)-2-oxolanecarboxylate; Terazosin Impurity 21
2-Tetrahydrofuroic acid is a colorless to yellow viscous liquid that turns brown when heated or stored for a long time. Boiling point 244 ℃ (736mmHg), flash point 139 ℃. The relative density is 1.1700. Easy to dissolve in water, chloroform, ethyl acetate, etc.
| Item | Specificatie |
| Boiling point | 128-129 °C13 mm Hg(lit.) |
| Dichtheid | 1.209 g/mL at 25 °C(lit.) |
| Smeltpunt | 21°C |
| flash point | 139 °C |
| weerstand | n20/D 1.46(lit.) |
| pKa | 3.60±0.20(Predicted) |
2-Tetrahydrofuroic acid can serve as an antagonist of the VLA-4 antigen and also as a chiral resolving agent for the important intermediate of the super influenza drug Xofluza; (S) 2-THFA is the main raw material for preparing chiral adjuvant (S) – acetyltetrahydrofuran, an intermediate for preparing cephalosporin antibiotics, and an important intermediate for preparing hormone releasing hormone LHRH.
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