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Product name:Toltrazuril
Cas:69004-03-1
Molecular weight:425.38
Appearance: White or off-white moldable powder
EINECS：614-893-5
Synonyms:Toltrazuril, >=99%; bay-i9142; TOLTRAZURIL; 1-METHYL-3-[3-METHYL-4-[4-(TRIFLUOROMETHYLTHIO)PHENOXY]PHENYL]-1,3,5-TRIAZINE-2,4,6 (1H,3H,5H)-TRIONE; Bayvi 9142;
1.What is Toltrazuril？
Toltrazuril is a triazone compound and a new broad-spectrum special anti-coccidial drug. Toltrazuril is a white or off-white crystalline powder; odorless. Soluble in ethyl acetate or methylene chloride, slightly soluble in methanol, insoluble in water.
Spécification
| Apparence | Should be white or almost white crystalline powder, odorless | Almost white crystalline powder, odorless |
| Solubleness | Should dissolved in the ethylacetate orchloroform, sparingly soluble in methanol, insoluble in water | Dissolved in the ethylacetate or chloroform, sparingly soluble in methanol, insoluble in water |
| Point de fusion | 193℃-196℃ | 194℃-195℃ |
| IR | Should be concordant with the RS spectrum | Concordant with theRS spectrum |
| HPLC | The retention time of the main peak of the test solution should be consistent with that of the control solution | Consistent with that of the control solution |
| Clarity & color | Should be colorless and clear. If it is turbid, it shall not be more intense than standard turbidity solution No. 1.If the color is developed, it shall not be darker than the standard yellow colorimetric solution No.1. | Incolore et clair |
| Fluorides | ≥12.0% | 12.5% |
| Perte sur le séchage | ≤0,5% de | 0.04% |
| Résidu sur l'allumage | ≤0.1% | 0.02% |
| Les métaux lourds | ≤0.001% | <0.001% |
| Assay (Dry) | ≥98% | 99.6% |
Application
1.The mechanism of action of Toltrazuril is to interfere with coccidial cell nuclear division and mitochondria, affect the respiratory and metabolic functions of the worm, and can cause the endoplasmic reticulum to expand and cause severe vacuolization, thus causing the death of coccidia. It mainly affects coccidia. The stages of schizogeny and gametogenesis.
2. Toltrazuril often used as anticoccidial drugs. For the treatment of poultry coccidiosis. This product is effective against Eimeria in chickens, brucella, giant, tender, poisonous and mild; Eimeria in turkeys, Eimeria in turkeys; and Eimeria in geese. It has good inhibitory effect on Eimeria truncatula and Eimeria truncatula.
3. Toltrazuril is an antiprotozoal drug that acts against coccidial parasites. Toltrazuril induces changes in the subtle structure of coccidia during development, mainly due to swelling of the endoplasmic reticulum and Golgi apparatus and abnormalities in the surrounding nuclear space, which interferes with nuclear division. Toltrazuril causes a reduction in parasite respiratory enzymes.
Emballage
1kg/bag,25kg/drum
