Was Ist Daptomycin With Cas No 103060-53-3
Datomicin is a new structured cyclic lipopeptide antibiotic extracted from the fermentation broth of Streptomyces. In addition to acting on most clinically relevant gram-positive bacteria, it is more important that it has strong activity in vitro against isolated strains that have shown resistance to methicillin, vancomycin and linezolidine, This characteristic has very important clinical significance for critically infected patients.
1.Quick Details of Daptomycin
CAS:103060-53-3
Synonyms: N-[N- (1-Oxodecyl)- L-Trp-D-Asn-L-Asp-]-cyclo [L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser- [(3R)-3-methyl-L-Glu-] -4-(2-aminophenyl)-4-oxo-L-Abu-]; N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-]; N-(1-OxodChemicalbookecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α, 2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone; DAPTOMYCINE; Dapcin;Daptomycin,>=99%; DaptomycinReadyMadeSolution; Daptomycin(LY146032)
Molecular Formula:C72H101N17O26
Molecular Weight:1620.67
Appearance: Light yellow to yellow powder
EINECS:600-389-2
Product Categories: Organic Chemistry;Nutrition Health
2. Specification of Daptomycin
| Produkt Name: | Daptomycin | Chargen-Nr. | JL20220811 |
| Cas | 103060-53-3 | MF Date | Aug. 11, 2022 |
| Verpackung | 1KG/BAG | Analyse-Datum | Aug. 11, 2022 |
| Menge | 100KGS | Ablaufdatum | Aug. 10, 2024 |
| IchTEM
分析项目 |
SSTANDARD
技术指标 |
ERGEBNIS
实测结果 |
|
| Aussehen | Light yellow to yellow powder | Entsprechen | |
| 气味 | Geruchlos | Entsprechen | |
| Assay | ≥95.0% | 97.9% | |
| Specific optical rotation | +15.5～+20.5 | +16.8 | |
| Klarheit ofsolution | Clarified | Clarified | |
| PH-Wert | 3.0～4.5 | 3.2 | |
| Rückstand auf Zündung | ≤0.2% | 0.1% | |
| Wasser | ≤5.0% | 2.4% | |
| Lactone hydrolysate | ≤0.80% | 0.08% | |
| β-isomer | ≤1.5% | 0.1% | |
| RS-5/6 | ≤0.80% | 0.06% | |
| RS-7 | ≤0.80% | Nicht erkannt | |
| RS-7a/7b | ≤0.20% | 0.07% | |
| Anhydrodaptomycin | ≤2.0% | 0.8% | |
| Other individual | ≤0.15% | Nicht erkannt | |
| Total impurities | ≤5.0% | 1.1% | |
| Ethyl alcohol | ≤0.5% | 0.0% | |
| Acetic acid | ≤0.5% | Nicht erkannt | |
| Bakterielle endotoxins(EU/mg) | ≤0.28 | <0.28 | |
| Aerobic bacteria(cfu/g) | ≤1000 | <10 | |
| Mold &yeast(cfu/g) | ≤100 | <10 | |
| E. coil | Nicht erkannt | Nicht erkannt | |
| Conclusion | Qualified | ||
3. Application of Daptomycin
Medical intermediate for the treatment of concurrent skin and skin structure infections caused by some gram-positive and sensitive strains.
4. Packing of Daptomycin
1kgs Tasche oder als Anforderung der Kunden. Halten Sie es Weg von Licht bei einer Temperatur unter 25℃.
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