1.Quick Details of Daptomycin
CAS:103060-53-3
Synonyms: N-[N- (1-Oxodecyl)- L-Trp-D-Asn-L-Asp-]-cyclo [L-Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser- [(3R)-3-methyl-L-Glu-] -4-(2-aminophenyl)-4-oxo-L-Abu-]; N-[N-Decanoyl-L-Trp-D-Asn-L-Asp-]-cyclo[Thr*-Gly-L-Orn-L-Asp-D-Ala-L-Asp-Gly-D-Ser-[(3R)-3-methyl-L-Glu-]-3-(2-aminobenzoyl)-L-Ala-]; N-(1-OxodChemicalbookecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α, 2-diamino-γ-oxo-benzenebutanoicacid(13-4)lactone; DAPTOMYCINE; Dapcin;Daptomycin,>=99%; DaptomycinReadyMadeSolution; Daptomycin(LY146032)
Molecular Formula:C72H101N17O26
Molecular Weight:1620.67
Appearance: Light yellow to yellow powder
EINECS:600-389-2
Product Categories: Organic Chemistry;Nutrition Health
2. Specification of Daptomycin
| Product Name: | Daptomycin | Batch No. | JL20220811 |
| Cas | 103060-53-3 | MF Date | Aug. 11, 2022 |
| Packing | 1KG/BAG | Analysis Date | Aug. 11, 2022 |
| Quantity | 100KGS | Expiry Date | Aug. 10, 2024 |
| ITEM
分析项目 |
STANDARD
技术指标 |
RESULT
实测结果 |
|
| Appearance | Light yellow to yellow powder | Conform | |
| Odor | Odorless | Conform | |
| Assay | ≥95.0% | 97.9% | |
| Specific optical rotation | +15.5～+20.5 | +16.8 | |
| Clarity ofsolution | Clarified | Clarified | |
| PH | 3.0～4.5 | 3.2 | |
| Residue on ignition | ≤0.2% | 0.1% | |
| Water | ≤5.0% | 2.4% | |
| Lactone hydrolysate | ≤0.80% | 0.08% | |
| β-isomer | ≤1.5% | 0.1% | |
| RS-5/6 | ≤0.80% | 0.06% | |
| RS-7 | ≤0.80% | Not detected | |
| RS-7a/7b | ≤0.20% | 0.07% | |
| Anhydrodaptomycin | ≤2.0% | 0.8% | |
| Other individual | ≤0.15% | Not detected | |
| Total impurities | ≤5.0% | 1.1% | |
| Ethyl alcohol | ≤0.5% | 0.0% | |
| Acetic acid | ≤0.5% | Not detected | |
| Bacterial endotoxin(EU/mg) | ≤0.28 | <0.28 | |
| Aerobic bacteria(cfu/g) | ≤1000 | <10 | |
| Mold &yeast(cfu/g) | ≤100 | <10 | |
| E.coil | Not detected | Not detected | |
| Conclusion | Qualified | ||
3. Application of Daptomycin
Medical intermediate for the treatment of concurrent skin and skin structure infections caused by some gram-positive and sensitive strains.
4. Packing of Daptomycin
1kgs bag or requirement of clients. Keep it away from light at a temperature below 25℃.
