CAS:13553-79-2
Molecular Formula:C37H45NO12
Molecular Weight:2695.75
EINECS:236-938-4
Synonyms:Rifaximin impurity E (EP); Rifaximin Impurity 5 (Rifaximin EP Impurity E); Rifamycin, 1,4-dideoxy-1,4-dihydro-1,4-dioxo-; Rifaximin EP Impurity E; rifamycin; Rifamycin S CRS; Rifamycin Impurity 2(Rifamycin EP Impurity B)（Rifamycin S); Rifamycin S USP/EP/BP
Rifamycin S is the third-generation product of the rifampicin class of drugs, which has high efficacy and broad-spectrum antibacterial activity. It has a high sensitivity to various clinically common drug-resistant bacteria. Lipomycin B undergoes oxidation, reduction, and hydrolysis to produce rifampicin sodium.
| البند | مواصفات |
| نقطة الغليان | 700.89°C (rough estimate) |
| الكثافة | 1.2387 (rough estimate) |
| نقطة انصهار | 179-181°C (dec.) |
| pKa | 3.85±0.70(Predicted) |
| المقاومة | 1.6630 (estimate) |
| ظروف التخزين | -20°C Freezer |
Rifamycin S is used as a pharmaceutical intermediate to inhibit the activity of bacterial RNA polymerase. Obstructing bacterial RNA synthesis, ultimately blocking the synthesis of proteins required by bacteria, leading to bacterial death and exhibiting bactericidal effects.
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