What is nonivamide used for

What is nonivamide？

Nonivamide, also known as capsaicin, is the active ingredient of the red pepper plant. It is irritating to mammals, including humans, and can create a burning sensation in the skin. The molecular formula of capsaicin is C17H27NO3, molecular weight is 293.4, cas 2444-46-4. This compound has water-repellent lipophilic properties and is colorless and odorless crystalline or waxy compound. Nonivamide is not only found in red pepper, but also widely used in food, medicine and other industrial fields, and has attracted attention for its unique spicy taste and physiological activity. In addition, Nonivamide has some potential health benefits, such as helping with weight loss, which makes it an important object for scientific research and technological development.

Nonivamide is a natural alkaloid. It is a highly volatile, lipophilic and hydrophobic white crystalline powder 85% to 95% of nonivamide can be rapidly absorbed through the gastrointestinal tract. After absorption, nonivamide is mainly metabolized by liver cytochrome enzyme P450, and a small part is hydrolyzed in the small intestine. Metabolites are excreted mainly through the kidneys, and a small part is excreted in the form of prototype feces and urine. After systemic administration, capsaicin concentrations were higher in the brain, spinal cord and liver.

What is nonivamide used for?

Military field: nonivamide has important military applications as a rodent repellent, helping to prevent damage to military installations.

Pharmaceutical field: The application of nonivamide in the pharmaceutical field includes analgesia without addiction, inhibition of bacteria and fungi, and promotion of blood circulation. Nonivamide can be made into a rub, tincture, cream, patch and other forms.

Agricultural field: nonivamide as an expelling agent, the use of its strong tear-jerking effect, used in the manufacture of tear-jerking and other expelling equipment, personal defense articles, widely used in agriculture to expel pests and wildlife.

Marine antifouling field: nonivamide is used as a biological antifouling agent, has been used in Marine antifouling coatings, coated on ships and Marine buildings in contact with the seawater to prevent the attachment of algae, shellfish, mollusks and other Marine organisms, in order to prevent the accumulation of aquatic organisms in the hull of the purpose of replacing the traditional organotin antifouling coatings.

Cosmetics and health care products: nonivamide is widely used in food, health care products, cosmetics and other fields, its tear-inducing properties make it an ideal ingredient in these fields.

In addition, nonivamide also has pharmacological effects such as analgesic, anti-inflammatory, frostbite, antipruritic, bactericidal, drug rehabilitation, etc. It should be stored at low temperature, and long-term exposure to air will lead to reduced content.

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