Madecassic acid with CAS 18449-41-7

what is of Madecassic acid with CAS 18449-41-7?

Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E₂ (PGE₂; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.

CAS: 18449-41-7

MF: C30H48O6

Purity: 99%

1.Quick details of Madecassic acid with CAS 18449-41-7


Type:Herbal Extract Form:Powder Variety:Centella Asiatica Extract Part:Other Extraction Type:Liquid-Solid Extraction Packaging:bottle, CAN, Drum, Glass Container, Mason Jar, Plastic Container, Vacuum Packed Place of Origin:China Grade:Food $ Medical Grade Brand Name:Unilong Model Number:JL20211776 Density:1.23 Boiling Point::270°C (dec.) boiling point:641.7 °C at 760 mmHg flash point:355.9 °C PSA::118.22000 logP::4.00350 pka:4.63±0.70(Predicted) MOQ:25Kilograms Package:25kg/drum

2.Description of Madecassic acid with CAS 18449-41-7

Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells.

4.Packing

25kgs/drum,9tons/20’container

25kgs/bag,20tons/20’container

Items	Standards	Results
Appearance	powder	Conforms
Odor	Characteristic	Conforms
Assay	98%	Conforms
Loss on Drying	≤2.0%	0.09%
Mesh Side	80 mesh	Conforms
PH Value	1.8-2.3	2.10
Optical Rotation	-30°-34°	-32°
Residue on ignition	≤2.0%	0.12%

Madecassic acid with CAS 18449-41-7

Madecassic acid with CAS 18449-41-7

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