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聚龙新材料科技（山东）有限公司
Unilong Industry Co.,Ltd.

聚龙新材料科技
Unilong Industry

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  • Madecassic acid with CAS 18449-41-7
    • Madecassic acid with CAS 18449-41-7

    Madecassic acid with CAS 18449-41-7

    what is of  Madecassic acid with CAS 18449-41-7?

    Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.

    Category

    1.Quick details of  Madecassic acid with CAS 18449-41-7

    Type:Herbal Extract
    Form:Powder
    Variety:Centella Asiatica Extract
    Part:Other
    Extraction Type:Liquid-Solid Extraction
    Packaging:bottle, CAN, Drum, Glass Container, Mason Jar, Plastic Container, Vacuum Packed
    Place of Origin:China
    Grade:Food $ Medical Grade
    Brand Name:Unilong
    Model Number:JL20211776
    Density:1.23
    Boiling Point::270°C (dec.)
    boiling point:641.7 °C at 760 mmHg
    flash point:355.9 °C
    PSA::118.22000
    logP::4.00350
    pka:4.63±0.70(Predicted)
    MOQ:25Kilograms
    Package:25kg/drum

    2.Description of Madecassic acid with CAS 18449-41-7

    Items
    Standards
    Results
    Appearance
     powder
    Conforms
    Odor
    Characteristic
    Conforms
    Assay
    98%
    Conforms
    Loss on Drying
    ≤2.0%
    0.09%
    Mesh Side
    80 mesh
    Conforms
    PH Value
    1.8-2.3
    2.10
    Optical Rotation
    -30°-34°
    -32°
    Residue on ignition
    ≤2.0%
    0.12%
    3.Application 

    Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells.

    4.Packing 

    25kgs/drum,9tons/20’container

    25kgs/bag,20tons/20’container

     

    COA 1-Methylcyclopropene

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