1-Chloorethyl chloroformate CAS 50893-53-3

Wat is 1-Chloorethyl chloroformate CAS 50893-53-3？

1-Chloorethyl chloroformate is een kleurloze vloeistof met een scherpe geur; Oplosbaar in alcohol, ether, aceton, wasbenzine en andere oplosmiddelen; onoplosbaar in water ontleedt in water. Kookpunt 153 ℃ (10108Pa), n 20D=1.441. 1-Chloorethyl chloroformate is een kleurloze of licht gekleurd transparant olieachtige vloeistof met een kookpunt van 118-119 ℃.

1-Chloroethyl chloroformate is a specialized organic intermediate widely used in pharmaceutical synthesis and fine chemical manufacturing. With CAS 50893-53-3, this high-purity compound plays a critical role as a protecting agent and key reagent in advanced chemical reactions, especially in esterification and carbamate formation.

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Specificatie

Applications of 1-Chloroethyl Chloroformate (CAS 50893-53-3)

1-Chloroethyl chloroformate CAS 50893-53-3 is a highly valuable specialty chemical intermediate used intensively across pharmaceutical synthesis, agrochemicals, fine chemicals, and polymer chemistry. Its strong acylation and protective reactivity make it an essential building block in advanced organic reactions.

1. Pharmaceutical & API Manufacturing

A key reagent in the synthesis of numerous active pharmaceutical ingredient (API) intermediates, especially where carbamate and ester-functional groups are required.

Typical uses:

• Protecting group reagent for alcohols and amines

• Synthesis of urethane derivatives

• Preparation of β-lactam antibiotic intermediates

• Fragment assembly in peptide chemistry

2. Organic Synthesis & Fine Chemicals

Acts as an effective chloroformylation and carbamoylation reagent in organic chemistry.

Functions:

• Protection of amine groups under mild reaction conditions

• Key intermediate for carbamates, chloroformates, and other ester derivatives

• Used in multi-step synthesis routes for specialty fine chemicals

3. Agrochemical & Pesticide Intermediate Production

Widely used in agrochemical research and manufacturing, particularly in the synthesis of:

• Herbicide intermediates

• Pesticide active intermediates

• Specialty crop-protection reagents

Ensures high molecular stability and reaction control in downstream processing.

4. Polymer & Material Chemistry

1-Chloroethyl chloroformate is utilized in advanced material synthesis, including:

• Special urethane-based polymers

• Modified polycarbonates

• Functionalized coatings additives

• Specialty adhesives & elastomers

These derivatives improve material durability, adhesion, and flexibility.

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