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CAS: 7149-65-7
Molecular Formula: C7H11NO3
Molecular Weight: 157.17
EINECS: 230-480-9
Synonyms: ETHYL L-PYROGLUTAMATE; ETHYL (S)-PYROGLUTAMATE; ETHYL (S)-2-PYRROLIDINONE-5-CARBOXYLATE; ETHYL (S)-(+)-2-PYRROLIDONE-5-CARBOXYLATE; ETHYL (S)-2-PYRROLIDONE-5-CARBOXYLATE; H-PYR-OET; ethyl 5-oxo-L-prolinate; (S)-(+)-5-Ethylcarboxyl-2-pyrrolidinone
Ethyl L-pyroglutamate CAS 7149-65-7 is a low melting point solid with a white to creamy color. It is a non natural amino acid derivative that has been used for protein modification in bacteria, yeast, and mammalian cells. It has applications in basic research, drug development, biotechnology, and other fields, and is widely used for detecting protein structural changes, drug coupling, biosensors, and other applications.
| Voce | Specifica |
| Condizioni di conservazione | Conservare in luogo buio |
| Densità | 1.2483 (stima approssimativa) |
| Punto di fusione | 54-56 °C |
| pKa | 14.78±0.40(Previsto) |
| MW | 157.17 |
| attività ottica | [α]19/D +3.3°, c = 10 in etanolo |
Etilico L-pyroglutamate può essere utilizzato come farmaco molecola attiva e organica sintesi di intermedi, come ad esempio per la sintesi della molecola biologicamente attiva HIV inibitori della integrasi. Nel sintetico di conversione, l'atomo di azoto dell'ammide gruppo può essere accoppiato con iodobenzene, o a idrogeno sull'atomo di azoto, può essere convertito in un atomo di cloro. In aggiunta, gruppi estere possono essere convertiti in ammide prodotti attraverso aminoester reazioni di scambio.
Di solito confezionati in 25kg/drum,e può anche essere personalizzato pacchetto.
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