p-Toluenesulfonyl Isocyanate CAS 4083-64-1

p-Toluenesulfonyl Isocyanate CAS 4083-64-1 - Imagen 2

p-Toluenesulfonyl Isocyanate CAS 4083-64-1

CAS: 4083-64-1
Molecular Formula: C8H7NO3S
Molecular Weight: 197.21
Appearance: clear light liquid
EINECS: 223-810-8

Synonym: p-Toluenesulfonyl Isocyanate; 4-Isocyanatosulphonyltoluene,; p-Toluenesulfonylisocyanate,96%,AcroSeal; Isocyanicacid,anhydridewithp-toluenesulfonicacid(6CI); p-Toluenesulfonylisocyanate96%; p-Toluenesulfonylisocyanate,96%

what is p-Toluenesulfonyl Isocyanate CAS 4083-64-1

p-Toluenesulfonyl Isocyanate (CAS 4083-64-1), also known as toluene-4-sulfonyl-isocyanate or p-tosyl isocyanate, is an important organic intermediate widely used in the synthesis of pharmaceuticals, agrochemicals, and specialty polymers. This compound contains both an isocyanate group (-NCO) and a sulfonyl group (-SO₂-), providing strong reactivity and selectivity in organic reactions.

Its stable reactivity makes it valuable for introducing sulfonyl and carbamoyl functionalities into complex molecules. Because of its versatility and high purity, p-toluenesulfonyl isocyanate CAS 4083-64-1 is commonly used in industrial-scale chemical production.

Especificación

Elemento	Estándar
Ensayo	El 98%Min
NCO	20.89 Min
Color	20APHA Max
PTSC	1%Max.

Aplicaciones

P-toluenesulfonyl Isocyanate (‌PTSI) ‌ is also used as an intermediate in medicine or pesticide, and as a dehydrating agent in solvent, filler, pigment, etc., and is effectively applied in wet-cured one-component and conventional two-component polyurethane paint systems. ‌PTSI is widely used in chemical products as a dehydrating agent and also as a stabilizer in purified bisisocyanates to prevent their deterioration or discoloration.

Pharmaceutical Intermediates
p-Toluenesulfonyl isocyanate is frequently used to produce urea and carbamate derivatives in drug synthesis. It acts as a reagent for modifying amines and alcohols, allowing the creation of biologically active compounds and protective groups in organic chemistry.
Polymer and Coating Chemistry
In polymer chemistry, toluene-4-sulfonyl-isocyanate serves as a crosslinking agent and reactive modifier for polyurethane and polyurea materials, improving mechanical strength and chemical resistance.
Agrochemical Production
p-Tosyl isocyanate participates in the synthesis of active pesticide intermediates, herbicides, and fungicides. Its high reactivity helps form stable sulfonyl-urea structures, essential in modern crop protection formulations.
Analytical Reagents & Chemical Synthesis
Due to its strong electrophilic property, p-toluenesulfonyl isocyanate 4083-64-1 is used as a derivatization agent for amines, alcohols, and phenols in analytical chemistry and high-performance synthesis reactions.